- Viktor Gorlitzer Von Mundy, " Influence of Fluorine and Iodine on the Metabolism, Particularly on the Thyroid Gland," Muenchener Medicische Wochenschrift, Vol. 105, pp. 182-186 (1963);
- A. Benagiano, "The Effect of Sodium Fluoride on Thyroid Enzymes and Basal Metabolism in the Rat," Annali Di Stomatologia, Vol. 14, pp. 601-619 (1965);
- Donald Hillman, et al., " Hypothyroidism and Anemia Related to Fluoride in Dairy Cattle," Journal of Dairy Science, Vol. 62, No.3, pp. .416-423 (1979);
- V. Stole and J. Podoba, " Effect of Fluoride on the Biogenesis of Thyroid Hormones," Nature, Vol. 188, No. 4753, pp. 855-856 (1960);
- Pierre Galleti and Gustave Joyet, " Effect of Fluorine on Thyroid Iodine Metabolism and Hyperthyroidism," Journal of Clinical Endocrinology and Metabolism, Vol. 18, pp. 1102-1110 (1958)
Fluoride and the Thyroid Explored
November 04, 2003
Dr. Barry Durrant-Peatfield wrote to me recently to share his thoughts regarding the fluoride issue. He agreed to share his thoughts with my readers here at the site. "As you know, Thyroid UK had a Thyroid Awareness Week last week and apart from the first and successful conference, we handed in a petition to the Prime Minister, Mr Blair, at 10 Downing St, protesting against his proposed nationwide fluoridation of our water supplies, in view of especial damage to thyroid sufferers. We are however pretty sure that it ended up in the very large waste bin in the fine and ornate entrance hall. I don't believe that thyroid sufferers are sufficiently aware of the dangers of fluoride intake and I thought it might be helpful to expand on this issue. It is an enzyme poison. Enzymes are complex protein compounds that vastly speed up biological chemical reactions while themselves remaining unchanged. As you read this, there is occurring in all of us a vast multitude of these reactions to maintain life and produce the energy to sustain it. The chains of amino acids that make up these complex proteins are linked by simple compounds called amides; and it is with these that fluorine molecules react, splitting and distorting them, thus damaging the enzymes and their activity. Let it be said at once, this effect can occur at extraordinary low concentrations; even lower than the one part per million, which is the dilution proposed for fluoridation in our water supply. Moreover, fluorides are cumulative and build-up steadily with ingestion of fluoride from all sources, which include not just water but the air we breatheLight Sources www.light-sources.com
Select One... Get the sleep you need & savings you deserve 55 or older? You may be at increased risk for heart attack or stroke. Learn more. Breathe Easier - Free Offer Questions for your doctor at vytorin.com Cancer / Goiter / Nodules Buyer's Guide Before You Buy Top Picks Thyroid Disease 101 Diet/Weight Loss Information Center The Best Thyroid Books for Patients Product Reviews Tools Medical Encyclopedia Forums Help FREE Newsletter and the food we eat. The use of fluoride toothpaste in dental hygiene and the coating of teeth are further sources of substantial levels of fluoride intake. The body can only eliminate half of the total intake, which means that the older you are the more fluoride will have accumulated in your body. Inevitably this means the ageing population is particularly targeted. And even worse for the very young there is a major element of risk in baby formula made with fluoridated water and the extreme sensitivity of the very young to fluoride toxicity makes this unacceptable. Since there are so many sources of fluoride in our everyday living, it will prove impossible to maintain an average level of 1ppm as is suggested. What is the result of these toxic effects? First the immune system. The distortion of protein structure causes the immune proteins to fail to recognise body proteins, and so instigate an attack on them, which is Autoimmune Disease. Autoimmune diseases constitute a body of disease processes troubling many thousands of people: R/A, SLE, Asthma, Systemic Sclerosis are examples; but in my particular context today, thyroid antibodies will be produced which will cause Thyroiditis resulting in the common hypothyroid disease, Hashimoto's Disease and the hyperthyroidism of Graves' Disease. Musculoskeletal damage results further from the enzyme toxic effect; the collagen tissue of which muscles, tendons, ligaments and bones are made, is damaged. Rheumatoid illness, osteoporosis and deformation of bones inevitably follow. This toxic effect extends to the ameloblasts making tooth enamel, which is consequently weakened and then made brittle; and its visible appearance is of course dental fluorosis. The enzyme poison effect extends to our genes; DNA cannot repair itself, and chromosomes are damaged. Work at the University of Missouri showed genital damage, targeting ovaries and testes. Also affected is inter uterine growth and development of the foetus, especially the nervous system. And increased incidence of Down's Syndrome has been documented.
Fluorides are mutagenic. That is, they can cause the uncontrolled proliferation of cells we call cancer. This applies to cancer anywhere in the body; but bones are particularly picked out. The incidence of osteosarcoma in a study reporting in 1991 showed an unbelievable 50% increase.
A report in 1955 in the New England Journal of Medicine showed a 400% increase in cancer of the thyroid in San Francisco during the period their water was fluoridated. What concerns me so deeply is that in concentrations as low as 1ppm, fluorides damage the thyroid system on 4 levels.
1. The enzyme manufacture of thyroid hormones within the thyroid gland itself. The process by which iodine is attached to the amino acid tyrosine and converted to the two significant thyroid hormones, thyroxine (T4) and liothyronine (T3), is slowed.
2. The stimulation of certain of the G proteins whose function is to govern uptake of substances into each of the cells of the body, from the toxic effect of Chronic Dry Eye Chronic Pain Management Erectile Dysfunction Alzheimer's Disease What's Hot "Best" Thyroid Drug? Conjugated Linoleic Acid (CLA) Dr. Bruce Fife's Positive R... Is It Allergies or Sinusitis? -- May 2002 Hidden Danger fluoride, has the effect of switching off the uptake into the cell of the active thyroid hormone.
3. The thyroid control mechanism is compromised. The thyroid stimulating hormone output from the pituitary gland is inhibited by fluoride, thus reducing thyroid output of thyroid hormones.
4. Fluoride competes for the receptor sites on the thyroid gland which respond to the thyroid stimulating hormone; so that less of this hormone reaches the thyroid gland and so less thyroid hormone is manufactured. These damaging effects, all of which occur with small concentrations of fluoride, have obvious and easily identifiable effects on thyroid status. The running down of thyroid hormone means a slow slide into hypothyroidism. Already the incidence of hypothyroidism is increasing as a result of other environmental toxins and pollution together with wide spread nutritional deficiencies.
One further factor should occasion us deep anxiety. Professor Hume of Dundee, Scotland, in his paper given earlier this year to the Novartis Foundation, pointed out that iodine deficiency was growing worldwide. 141 million Europeans are at risk; only 5 European countries are iodine sufficient. The UK now falls into the marginal and focal category. (I do not know what the statistics are for the USA.) He recently produced figures to show that 40% of pregnant women in the Tayside region of Scotland were deficient by at least half of the iodine required for a normal pregnancy. A relatively high level of missing, decayed, filled teeth was noted in this non-fluoridated area, suggesting that the iodine deficiency was causing early hypothyroidism which interferes with the health of teeth. Dare one speculate on the result of now fluoridating the water?
These figures would be worrying enough, since they mean that iodine deficiency, which results in hypothyroidism (thyroid hormone cannot be manufactured without iodine) is likely to affect huge numbers of people. What makes it infinitely worse, is that fluorine, being a halogen, chemically related to iodine but very much more active, displaces iodine. So that the uptake of iodine is compromised by the ejection, as it were, of the iodine by fluorine. To condemn an entire population, already having marginal levels of iodine, to inevitable progressive failure of their thyroid system by fluoridating the water, borders on criminal lunacy. I would like to place a scenario in front of those who favour fluoridation. A new pill is marketed. Some trials, not all together satisfactory, nevertheless show a striking improvement in dental caries. Unfortunately, it has been found to be thyrotoxic, mutagenic, immunosuppressive, cause arthritis and infertility in comparatively small doses over a relatively short period of time. Do you think it should be marketed? Fluoridation of a nation's water supply will do little for dental health; but will have catastrophic affects on general health. We cannot, must not, dare not, subject nations to this appalling risk.
Studies dating back to the 1950s have shown links between Down's Syndrome and natural fluoridation. Ionel Rapaport also showed how the age of women bearing Down's Syndrome children decreased in direct relation to the increase of fluoride in the water supply. The more fluoride that was in the water, the younger the age of the women bearing Down's Syndrome children.
Is fluoride in part the reason for near epidemic levels of hypothyroidism in the United States? Some experts and researchers believe this is the case. Fluoride had been used for decades as an effective anti-thyroid medication to treat hyperthyroidism and was frequently used at levels below the current "optimal" intake of 1 mg/day. This is due to the ability of fluoride to mimic the action of thyrotropin (TSH). It makes sense, then that out of the over 150 symptoms and associations of hypothyroidism, almost all are also symptoms of fluoride poisoning. Researcher and advocate Andreas Schuld has also found that excess of fluoride correlates with other thyroid-related issues such as iodine deficiency. Fluoride and iodine, both being members of the halogens group of atoms, have an antagonistic relationship. When there is excess of fluoride in the body it can interfere with the function of the thyroid gland. It is possible that iodine deficiency, which is the most common cause of brain damage and mental diby simply cutting back on the use of fluoride.
Steyn writes in 1962 that drinking water containing as little as 1 to 2 ppm of fluorine can cause serious disturbances of general health and especially in normal thyroid gland function and in the normal processes of calcium-phosphate metabolism (parathyroid function).
Thyroid activity is reduced while bathing in fluoridated water, by absorption through the skin and inhalation.
One child dies every minute due to complications associated with fluorine-induced iodine deficiency.
Carpal Tunnel Syndrome can often be a result of hypothyrodism. Conditions that increase tissue edema such as hypothyroidism are well-known causes of Carpal Tunnel Syndrome. In 1998, Dr. Bob Carton wrote: "Based on Roholm's work and other recent studies, there is every reason to believe that the increasing number of people with carpal-tunnel syndrome and arthritis- like pains are due to the mass fluoridation of drinking water"
- EPA Scientists, 1998
In 1969 Siddiqui show small visible goiters in persons 14 to 17 years of age in India to be directly related to high fluoride concentrations in drinking water.
Willems et al (1972) document that sodium fluoride blocks thyroid hormone secretion.
Also in 1972 Day and Powell-Jackson studied 648 people in 13 mountaineous regions in Nepal where the iodine content in the water was low and found a close relationship between fluoride intake and the incidence of goiter.
The effects of fluoride on the thyroid gland have been studied so extensively, that it baffles the mind how experts on thyroid disease from Harvard or the University of Toronto can claim that fluorides do not affect thyroid gland function, especially when it has been used as medication to do just that! This stance just defies all knowledge properly gained in the last 70 years of related research. One cannot find any mention of fluorides in ANY current "official" thyroid disease related literature.
